Abstrakt

Utilization of cyanuric chloride in the synthesis of some novel chalcones and their derivatives

Kishor Kapadia, Pankit Solankee, Yogesh Prajapati, Hiral Patel, Sejal Solankee, Anjani Solankee

Base catalyzed condensation of 2,4-bis-(phenylamino)-6-(4'-acetyl phenylamino)-s-triazine (5) with different aromatic aldehydes yield chalcones (6a-e). These chalcones (6a-e) on cyclisation with hydrazine hydrate in presence of glacial acetic acid and malononitrile in presence of ammonium acetate give the corresponding acetylpyrazolines (7a-e) and cyanopyridines (8a-e) respectively. The constitutions of newly synthesised compounds have been established on the basis of their elemental analysis, IR and 1H NMR spectral data.