Abstrakt

Synthesis, characterization and antimicrobial screening of3-(1Hbenzo[ d]imidazol-2-ylsulfanyl)methyl-4-[phenoxy(phenyl)acetamido)-5-mercapto-1,2,4-triazole and related aryloxy compounds

Debojyoti Chakraborty, S.R.Sharma, MadhuBala, L.K.Mishra

Aseries of new1H-benzo[d]imidazole derivatives of 3,4-substituted triazole. 3-(1H-Benzo[d] imidazol -2-ylsul fanyl )methyl -4- [phenyloxy (phenylacetamido)]-5-mercapto-1,2,4-triazole and related aryloxy compounds were synthesised, analysed and characterised byFTIR, 1HNMRand elemental analysis. These compounds were screened for antibacterial and antifungal activity. The antibacterial activities were compared against chlorophenicol and antifungal activity with mycostalin. Some triazole derivatives showed positive antibacterial and antifungal activity.