Abstrakt

Synthesis, Characterization And Antimicrobial Activity Of Co(II),Ni(II), Cd(II), Zn(II), Pd(II), Rh(III) And Ru(III) Complexes Of 2-(2-Napthylthio)-Quinoline-3-Carboxaldehyde

B.Basavaraju, H.S.Bhojya naik, S.Shanmukhappa

A new bidentate ligand, 2-(2-napthylthio)-quinoline-3-carboxaldehyde(L) has been synthesized. Co(II), Ni(II), Cd(II), Zn(II), Pd(II), Rh(III) and Ru(III) complexes of the ligand have been prepared. The ligand is characterized by elemental analyses, infrared, UV, NMR and Mass spectral data and the metal chelates are characterized by elemental analyses, conductivity data, magnetic susceptibility measurements, infrared, 1H-NMR and UV-Vis spectral data. On the basis of the above data it is inferred that the ligand behaves as a bidentate NS chelating agent. The ligand and the metal chelates were screened for their anti microbial activity against the gram positive bacteria S.aureus and gram negative bacteria P.aerugenosa and the fungi C.albicans, A.flavus and A.niger. The results show that the complexes are potent antimicrobial than the parent ligand and also indicate that the inhibition activity increases with increase of concentration.