Abstrakt

Synthesis and screening of antimicrobial activity of N-(3 cyano -6phenothazie -10yl-4-phenyl –pyridine -2yl) actamide derivaties

Dinanath D.Patil, Dnyandeo K.Mhaske, Machindra A.Patare, Gurumeet C.Wadhawa

Phenothiazin and its derivatives posses diverse type of biological properties such as antiviral, antiphrastic, antiparkins, etc. They were synthesized by using chalcones of N – acetylphenothiazine. And the structures of these compounds were confirmed by IR, NMR (1H analysis. The newly synthesized compounds were also evaluated for antimicrobial activity against variety of bacterial Strains and some of these compounds have shown significant antibacterial and antifungal activities.