BioChemie: Eine indische Zeitschrift
ISSN (PRINT): 0974-7427

Abstrakt

Silicon tetrachloride-induced green and efficientMCRprotocol for the synthesis of 1,8-dioxo-decahydroacridines and their transformation to novel functionalized pyrido-tetrazolo[1,5-a]azepine derivatives

Hanan A.Soliman, Tarek A.Salama


Green and efficient MCR protocol for the synthesis of 1,8-dioxodecahydroacridine derivatives was achieved through a one-pot, threecomponent condensation of dimedone, aryl amines and aryl aldehydes utilizing tetrachlorosilane (TCS) as catalyst under solvent-free conditions. Reaction of the titled compoundswith TCS-NaN3 to give novel functionalized pyrido[3,2-c]tetrazolo[1,5-a]azepine derivatives is also described.


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