Abstrakt

Phenolic composition and biological activities of methanolic extract of strawberry leaves (Fragaria ananassa)

Amani M.D.El-Mesallamy, Sahar A.M.Hussein, Mohamed El.Gerby, Mohamed H.M.Abd El Azim

Our study aimed to evaluate antimicrobial, antioxidant and antitumor activities and currently phenolic of polar extract of Strawberry (Fragaria ananassa) leaves. Seventeen phenolic compounds were isolated from methanolic extract of Strawberry leaves and identified as hydrolysable tannins, flavanol, flavonol glycosides and phenolic acids. The antioxidant activity was measured by 2, 2' - Diphenyl Picrylhydrazyl (DPPH) radical scavenging method. The methanolic extract completely inhibitedDPPHat three different concentrations 19, 38, 77 µl which showed very high antioxidant capacity, which was close to ascorbic acid standard used. Antimicrobial activities of plant extracts were studied against five bacterial strains and five fungal species, 0.1 ml of plant extract (10 mg / 1 ml) had inhibitory effect for most bacterial spp. and showed no effect against all fungal spp., Clearly inhibitory effect was obtained against all of the tested bacterial and fungal strains at 0.3 ml (10mg /1 ml) of the extract. Themethanolic extract of strawberry leaveswas tested against three human cell lines; the extract has activity against all cell lines tested.