Analytische Chemie: Eine indische Zeitschrift
ISSN (PRINT): 0974-7419

Abstrakt

Pharmacological validation for sarasvata arista (An ayurvedic formulation) on maximal electro shock induced epileptic model.

P. Muralidharan, Balamurugan Gunasekaran


In the present study, anAyurvedic poly herbal formulation, Sarasvata arista (SVA) was validated for its protective effect against seizures during epileptic attacks.Atotal daily dose of 1.5ml/ 100 gramof rat was administered to the test animals.After 15 days, seizures were induced by Maximal Electro Shock (MES) and the duration of various phases of epilepsy were observed and compared with the control animals. A significant (P<0.01 and P<0.001) reduction in the time taken for righting reflex was noted. The levels of some of the biogenic amineswere also estimated and a significant level of restoration in dopamine, serotonin and nor adrenaline was observed in the forebrain region of epilepsy induced rats treated with SVA.


Haftungsausschluss: Dieser Abstract wurde mit Hilfe von Künstlicher Intelligenz übersetzt und wurde noch nicht überprüft oder verifiziert

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