Abstrakt

Immunological tolerance-inducing nanomedicines that target dendritic cells

Alina Catherine

A promising therapy for autoimmune disease has been demonstrated by induced tolerogenic dendritic cells in preclinical studies and disease models in the lab. Instead of using the immune system's cells and processes to suppress the autoreactive lymphocytes that cause disease and damage, tolerogenic immunotherapy makes use of those mechanisms. The fundamental techniques for isolating and reprogramming Dendritic Cells (DCs), the central component of this strategy, are well known.