Abstrakt

Antihyperglycemic Activity of Anogeissus Latifolia in Streptozotocin Induced Diabetic Rats

K. M. M. Parvathi, C. K. Ramesh, V. Krishna, M. Paramesha and I. J. Kuppast

The present investigations explores the antihyperglycemic potential of Anogeissus latifolia bark and leaf extracts by using solvents viz. petroleum ether, chloroform and methanol in streptozotocin induced diabetic albino rats. Streptozotocin was administered intraperitoneally at a dose of 65 mg/kg body weight. The administration of oral dose at 200 mg/kg body weight and 300 mg/kg body weight of methanolic bark and leaf extracts, respectively produced significant lowering of blood glucose level in streptozotocin induced diabetic rats. Hypoglycemic effects were compared with control. The results of present study revealed that the plant leaf and bark extracts of A. latifolia possess potent antihyperglycemic activity.